Alkylamino mercaptoalkylamides and their use as a reducing agent

Details Alkylamino mercaptoalkylamides and their use as a reducing agent Alkylamino mercaptoalkylamides and their use as a reducing agent

1992-05-15

1994-08-02

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 70, 424 72, 514616, 514626, 564154, 564197, 564198, C07C32300, C07C32341

Patent

active

053343778

ABSTRACT:
Alkylamino-mercaptoalkylamides have the formula ##STR1## where in A represents the divalent radical --(CH.sub.2).sub.n --, wherein n is a whole number ranging from 2 to 5, or the divalent radical --(CH.sub.2).sub.2 --O--(CH.sub.2).sub.2 --,
m is 0, 1 or 2,
R.sub.1 represents hydrogen or linear or branched lower alkyl having 1-5 carbon atoms,
R.sub.2 and R.sub.3, each independently, represent hydrogen or a linear or branched lower alkyl having 1-4 carbon atoms with the proviso that R.sub.2 and R.sub.3 are not hydrogen simultaneously and the salts of the compound of formula I as well as the corresponding disulfides with the exclusion of the disulfide in which A.dbd.--(CH.sub.2).sub.2 --, m.dbd.0, R.sub.1 and R.sub.2 .dbd.H and R.sub.3 .dbd.--C.sub.2 H.sub.5. The compound of formula I is used as a reducing agent in a cosmetic composition for the permanent deformation of hair.

REFERENCES:
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Oiry et al, Chemical Abstracts, vol. 118(1992)234432z.
Chemical Abstracts, vol. 92, 1980, p. 566, Abstract No. 163592h.
Journal of Medicinal Chemistry, vol. 29, 1986, pp. 2217-2225, Oiry et al: "Synthesis and Radioprotective Activity of New Cysteamine and Cystamine Derivatives".
Chemical Abstracts, vol. 66, 1967, p. 5382, Abstract No. 55749u.
European Journal of Medicinal Chemistry, vol. 23, 1988, pp. 257-266, Fatome et al: "Etude de Germathiazolidines et de Dithioacetals Germanies Derives de la Cysteamine et Methylcysteaine N-Substitutes: Synthese et Activite Radioprotectrice".
Chemical Abstracts, vol. 83, 1975, p. 512, Abstract No. 178363x.
Journal of Pharmaceutical Sciences, vol. 53, 1964, pp. 906-908, Foye et al: "Antiradiation Compounds V Alpha-Amino Acid Esters of 2-Mercaptoethylammine".

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