Alkyl substituted fluorescent compounds and conjugates

Details Alkyl substituted fluorescent compounds and conjugates Alkyl substituted fluorescent compounds and conjugates

1982-07-19

1984-11-06

Kight, John

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 2601125R, 2601127, 260121, 436546, 424 85, 424 88, 435 7, 435188, 435177, 435178, 525420, 549388, A61K 39385, C07G 700

Patent

active

044811365

ABSTRACT:
Fluorescent antigen conjugates are provided comprising antigens covalantly bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H-xanthen-3-one, wherein the 1- and 8-positions are unsubstituted. Also provided are novel fluorescent compounds absorbing at wavelengths in excess of 500 nm, having active functionalities for linking to the antigen. Finally, methods are provided for analyzing antigens in serum, whereby serum interference is avoided.

REFERENCES:
patent: 4174384 (1979-11-01), Ullman et al.
patent: 4331590 (1982-05-01), Bocuslaski et al.

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