Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1981-02-09
1988-02-16
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 76, 514 77, 558169, A61K 3166
Patent
active
047255889
ABSTRACT:
The composition of this invention is 1-O-alkyl-2-acetoyl-sn-glycero-3-phosphocholine, having the ionic structural formula; ##STR1## wherein R is saturated alkyl having 9-21 carbon atoms, or salts or hydrates of the composition. Preferably R has 13-19 carbon atoms and most preferably R has 15 carbon atoms. The composition of this invention is useful for reducing hypertension in warm-blooded animals, including humans, when administered either orally or by injection or innoculation, e.g., intravenous injection. The composition can be prepared from naturally occurring lipids or synthetically from commercially available material.
REFERENCES:
patent: 4329302 (1982-05-01), Hanahan et al.
Blank Merle L.
Byers Lawrence W.
Leach, deceased Byron E.
Muirhead Ernest E.
Snyder Fred L.
Barrack Irving
Hamel Stephen D.
Hightower Judson R.
Raymond Richard L.
The United States of America as represented by the United States
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