Alkyl N-(3-trifluoromethylphenyl)-anthranilate

Details Alkyl N-(3-trifluoromethylphenyl)-anthranilate Alkyl N-(3-trifluoromethylphenyl)-anthranilate

1978-02-02

1980-04-15

Evans, Joseph E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

560 47, A61K 31245, C07C10154

Patent

active

041984315

ABSTRACT:
N-(3-trifluoromethylphenyl)anthranilic acid esters represented by the formula (I): ##STR1## wherein R represents an alkyl group having 4 to 8 carbon atoms, are disclosed.
The esters are useful as anti-inflammatory agents, particularly for an external application, with reduced toxicity. These esters are of great importance as non-steroid type anti-inflammatory agents for topical administration.

REFERENCES:
patent: 3144387 (1964-08-01), Jones
patent: 3413339 (1968-11-01), Scherrer
patent: 3558690 (1971-01-01), Sallmann et al.
patent: 3767811 (1973-10-01), Sherlock
patent: 3855230 (1974-12-01), Water et al.
patent: 4029815 (1977-06-01), Sherlock et al.
patent: 4143151 (1979-03-01), Wagner et al.
Klebanov et al., Chem. Absts., vol. 82, 363p (1975).
Salimbeni et al., Chem. Absts., vol. 83, 274f (1975).
Manghisi et al., Chem. Absts., vol. 77, 114067(x) 1972).

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