Alkyl esters of polyene antibiotics

Details Alkyl esters of polyene antibiotics Alkyl esters of polyene antibiotics

1973-07-23

1976-02-03

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424115, A61K 3500

Patent

active

039365263

ABSTRACT:
The present invention provides a process for the preparation of alkyl esters of polyene antibiotics, wherein a polyene antibiotic is reacted with a diazoalkane in the presence of a basic substance.
The present invention also provides, as new materials, alkyl esters of polyene antibiotics in which the alkyl radical of the ester grouping contains 2 or more carbon atoms.

REFERENCES:
chemical Abstracts 54:2669(b) (1960).

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