Alkyl esters of polyene antibiotics

Details Alkyl esters of polyene antibiotics Alkyl esters of polyene antibiotics

1975-11-11

1977-07-26

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424115, 424120, 424122, H61K 3500

Patent

active

040383822

ABSTRACT:
The present invention provides a process for the preparation of alkyl esters of polyene antibiotics, wherein a polyene antibiotic is reacted with a diazoalkane in the presence of a basic substance.
The present invention also provides, as new materials, alkyl esters of polyene antibiotics in which the alkyl radical of the ester grouping contains 2 or more carbon atoms.

REFERENCES:
chemical Abstracts 73:35698t and 35699u (1970).
Chemical Abstracts 80:121291f (1974).

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