Alkyl esters of 4-chlorophenoxy-4-oxo-cycloalkyl-carboxylic acid

Details Alkyl esters of 4-chlorophenoxy-4-oxo-cycloalkyl-carboxylic acid Alkyl esters of 4-chlorophenoxy-4-oxo-cycloalkyl-carboxylic acid

1973-11-23

1976-01-06

Terapane, John F.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C 6976

Patent

active

039312887

ABSTRACT:
Tricyclic compounds of the formula ##SPC1##
Wherein R.sub.1 is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, trifluoromethyl, cyano, carbamoyl, carboxy, lower alkoxy carbonyl, nitro, amino, mono-lower alkylamino, di-lower alkylamino, acyl, acylamido, sulfamoyl, di-lower alkylsulfamoyl, or difluoromethylsulfonyl; R.sub.2 is hydrogen, lower alkyl, amino-lower alkyl, mono-lower alkyl-amino-lower alkyl, or di-lower alkylamino-lower alkyl; n and r are independently 1 or 2; and X is oxygen or sulfur, prepared, inter alia, from the correspondingly substituted phenol or thiophenol and haloketocyclohexane or pentane carboxylic acid ester, are described. The end products are useful as anti-inflammatory and anti-rheumatic agents.

REFERENCES:
ganguly et al., C.A. 42 5003b.
Rene et al., C.A. 59 7527g.
Miles et al., C.A. 69 105979d.

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