Alkyl and cycloalkylthiophenylalkylaminoalkanols, their salts an

Details Alkyl and cycloalkylthiophenylalkylaminoalkanols, their salts an Alkyl and cycloalkylthiophenylalkylaminoalkanols, their salts an

1976-08-30

1980-10-14

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

2605706, A61K 31135, C07C 9106

Patent

active

042281873

ABSTRACT:
Amino-alcohols of the formula ##STR1## wherein R.sub.1 represents either a linear or branched chain alkyl radical having 1 to 4 carbon atoms, or a cycloalkyl radical having 5 or 6 carbon atoms; R.sub.2 represents a lower alkyl radical having 1 or 2 carbon atoms; R.sub.3 represents a linear or branched chain alkyl radical having 3 to 10 carbon atoms which radical is optionally substituted by phenyl; R.sub.4 represents hydrogen, or, together with R.sub.3 and the adjacent nitrogen atom, a heterocyclic nucleus of the piperidine type and the corresponding non-toxic salts of said amino-alcohols; preparation of the above and their use as antispasmodic, peripheral vasodilatory and anti-hypertensive agents and as an agent having a protective activity against anoxia of the myocardium.

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