Alkyl 5,6-dichloro-3,4-dihydro-2(1H)-iminoquinazoline-3-acetate

Details Alkyl 5,6-dichloro-3,4-dihydro-2(1H)-iminoquinazoline-3-acetate Alkyl 5,6-dichloro-3,4-dihydro-2(1H)-iminoquinazoline-3-acetate

1978-04-10

1979-03-27

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

2605709, 260575, 544250, C07D23984

Patent

active

041467183

ABSTRACT:
The known blood platelet antiaggregative agent 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one is prepared in high yield via an improved process involving a novel intermediate of the Formula ##STR1## in which R.sup.1 is (lower)alkyl and X is bromo, chloro or iodo. Two processes for the preparation of compounds of the Formula III are disclosed, one of which involves the novel intermediate ##STR2##

REFERENCES:
patent: 3932407 (1976-01-01), Beverung et al.

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