Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-05-02
2006-05-02
Morris, Patricia L. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S119000
Reexamination Certificate
active
07037923
ABSTRACT:
The present invention relates to novel alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines, to intermediates and methods for their preparation, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the present invention are potent inhibitors of MAP kinases, preferably p38 kinase. They are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
REFERENCES:
patent: 5716955 (1998-02-01), Adams et al.
patent: 5716972 (1998-02-01), Adams et al.
patent: 5717100 (1998-02-01), Selnick et al.
patent: 5756499 (1998-05-01), Adams et al.
patent: 5777097 (1998-07-01), Lee et al.
patent: 6288062 (2001-09-01), Adams et al.
patent: 6696464 (2004-02-01), McClure et al.
patent: 1247810 (2002-10-01), None
patent: 9901449 (1999-01-01), None
patent: 9961440 (1999-12-01), None
patent: 0006563 (2000-02-01), None
patent: 0031065 (2000-06-01), None
patent: 0035911 (2000-06-01), None
patent: 0040243 (2000-07-01), None
patent: 0041698 (2000-07-01), None
patent: 0063204 (2000-10-01), None
patent: 0272576 (2002-09-01), None
patent: 0272579 (2002-09-01), None
The Journal of Biological Chemistry, vol. 271, No. 40, pp. 24313-24316 (1996).
Bioorganic & Medicinal Chemistry Letters, 10, pp. 2047-2050 (2000); and.
Bioorganic & Medicinal Chemistry Letters, 11, pp. 9-12 (2001).
Dombroski Mark A.
Letavic Michael A.
McClure Kim F.
Ashbrook Charles
Lappin Julie M.
Morris Patricia L.
Pfizer Inc.
Slavinsky Christopher W.
LandOfFree
Alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3575270