Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1982-09-15
1984-01-17
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
260463, 560 40, 562445, C07C10177, A61K 31265
Patent
active
044263910
ABSTRACT:
Novel prodrugs of methyldopa which are [(alkoxycarbonyl)oxy]alkyl esters of methyldopa are disclosed. Also, pharmaceutical compositions containing these compounds are disclosed. Upon administration to warm-blooded animals, these prodrugs liberate methyldopa along with innocuous side products.
REFERENCES:
patent: 3939270 (1976-02-01), Ekstrom et al.
patent: 3983138 (1976-09-01), Saari
Saari et al., J. Med. Chem., vol. 21, 746-753, (1978).
Saari, Chem. Abs. 83:10873q (1975).
Isaka et al., Chem. Abs. 84:74168s (1976).
Ekstrom et al., Chem. Abs. 87:53266u (1977).
Alexander Jose
Shih Chung
Daus Donald G.
Kalita C.
Merck & Co. , Inc.
Monaco Mario A.
Sudol, Jr. Michael C.
LandOfFree
[(Alkoxycarbonyl)oxy]alkyl esters of methyldopa does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with [(Alkoxycarbonyl)oxy]alkyl esters of methyldopa, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and [(Alkoxycarbonyl)oxy]alkyl esters of methyldopa will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-700546