Alkoxy cycloalkanol esters of dihydrolysergic acid useful as 5HT

Details Alkoxy cycloalkanol esters of dihydrolysergic acid useful as 5HT Alkoxy cycloalkanol esters of dihydrolysergic acid useful as 5HT

1985-10-01

1987-12-22

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 69, A61K 3148, C07D45704

Patent

active

047147040

ABSTRACT:
Alkoxycycloalkyl esters of 1-substituted-6-C.sub.1-4 straight chain alkyl (or allyl)ergoline-8.beta.-carboxylic acids, useful as 5HT receptor antagonists.

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Cohen et al., ibid, 232, 770 (1984) (Cohen II)).
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Cohen et al., Drug Dev. Res., 5, 313 (1985) (Cohen IV).
Hingten et al., Abstract 37.4, Soc. for Neurosci. (13th Annual Meeting, Nov., 1983).

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