Alkenecarboxylic acid compounds

Details Alkenecarboxylic acid compounds Alkenecarboxylic acid compounds

1993-05-14

1995-07-25

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546248, 546335, 549 77, 562427, 562430, 562439, 562443, 562444, 562449, 562503, 562504, 562505, 562507, 562556, 562560, 554 88, 554106, 554110, C07D21104, A61K 31445

Patent

active

054363438

ABSTRACT:
Compounds of formula (I): ##STR1## in which: R.sub.1 and R.sub.2, which may be identical or different, represent a linear or branched (C.sub.1 C.sub.6) alkyl radical, a substituted or unsubstituted phenyl radical, a pyridyl radical or a thienyl radical, or, with the carbon atom to which they are attached, a substituted or unsubstituted (C.sub.4 -C.sub.7) cycloalkyl ring,
R.sub.3 represents

REFERENCES:
patent: 4948808 (1990-08-01), Witte et al.
patent: 4981873 (1991-01-01), Witte et al.
patent: 5280043 (1994-01-01), Cooper et al.
Vemylen et al., Thromboxane Synthase Inhibitors and Receptor Antagonists, Cardiovascular Drugs and Therapy 1992:6, 29-33 (1992).
Smith, Role of Thromboxane Receptor Antagonists in Cardiovascular Disease, in Prostaglandins in Clinical Research: Cardiovascular System, 29-38 (Mar. 1989).
McKenniff et al., BAY u3405, a Potent and Selective Thromboxane A.sub.2 Receptor Antagonist on Airway Smooth Muscle In Vitro, Br. J. Pharmacol. 104, 585-590 (Aug. 1991).
Ogletree et al., Pharmacological Profile of BMS 180,291: A Potent, Long-Acting, Orally Active Thromboxane A.sub.2 / Prostaglandin Endoperoxide Receptor Antagonist, The Journal of Pharmacology and Experimental Therapeutics 264 No. 2, 570-578 (May 1993).

Affiliated with

Also associated with

Rating

Alkenecarboxylic acid compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alkenecarboxylic acid compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkenecarboxylic acid compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-740472