Alkene, alkyne or cycloalkylene derivatives

Details Alkene, alkyne or cycloalkylene derivatives Alkene, alkyne or cycloalkylene derivatives

1989-04-14

1992-01-28

Brust, Joseph P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514678, 514679, 514685, 514708, 514709, 514713, 514710, 558413, 558414, 558415, 558423, 568 27, 568 28, 568 29, 568 31, 568 32, 568 33, 568 39, 568 43, 568 45, 568 49, 568 50, 568 52, 568 55, C07C25550, A61K 31275, A61K 31045, A61K 3110

Patent

active

050844784

ABSTRACT:
A compound of the formula ##STR1## wherein X has the formula --CR.sup.5 .dbd.CR.sup.6 --, --C.tbd.C-- or ##STR2## wherein ring A is phenyl, naphthyl or heterocyclic; wherein R.sup.1 is hydrogen, alkyl, alkanoyl or aroyl;

REFERENCES:
patent: 4070374 (1978-01-01), Chalk et al.
patent: 4139561 (1979-02-01), Onopchenko et al.
patent: 4191775 (1980-03-01), Glen
patent: 4239776 (1980-12-01), Glen et al.
patent: 4282218 (1981-08-01), Glen et al.
patent: 4386080 (1983-05-01), Crossley et al.
patent: 4507140 (1985-03-01), Sugavanam
patent: 4532341 (1985-07-01), Holmwood et al.
M. Parameswara Reddy, G. S. Krishna Rao, Synthesis, Oct. 1980, pp. 815-818.
J. Morrow Steward and D. W. Woolley, Biochemistry, "Antimetabolites of Mevalonic Acid. II. Inhibition of Ergosterol Synthesis in Yeast", vol. 3, No. 12, Dec., 1964, pp. 1998-2004.
C.A. 104: 129612w, Hughes et al. (1986).

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