Alkanolaminoxy derivatives of 3,4-dihydro-2H-1,4-benzothiazin-3-

Details Alkanolaminoxy derivatives of 3,4-dihydro-2H-1,4-benzothiazin-3- Alkanolaminoxy derivatives of 3,4-dihydro-2H-1,4-benzothiazin-3-

1983-10-18

1985-08-13

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544 52, A61K 3138, C07D27910

Patent

active

045350795

ABSTRACT:
Object of the invention is a class of new organic compounds derived from 1,4-benzothiazine through substitution of an hydrogen atom in position 6, 7 or 8 by an oxypropanolammine radical monosubstituted in N and furthermore a series of new phenyl derivatives of 1,4-benzothiazine, obtained as intermediate in the synthesis of oxypropanolammine derivatives, and process for obtained the new compounds in form suitable for the preparation of pharmaceutical compositions having antihypertensive, vasodilating and antiarrhythmic activity.

REFERENCES:
patent: 3337628 (1967-08-01), Crowther et al.
Troxler, Merck Index, Ninth ed., 1976, Merck and Co., N.J., p. 968, 7240.
Morrison et al., Morrison and Boyd Textbook of Organic Chemistry, Allyn and Bacon, 1978, pp. 767-769.
Chemical Abstracts, vol. 95, No. 13, Sep. 28, 1981, p. 711, No. 115577x, Columbus, Ohio, US & JP A 8151465 (Yoshitomi Pharmaceutical Industries, Ltd.), 09/05/1981, *Abstract.
Chemical Abstracts, vol. 97, No. 3, Jul. 19, 1982, p. 712, No. 23776z, Columbus, Ohio, US & JP-A8221377 (Shionogi and Co., Ltd.), 04-02-1982, *Abstract.
Journal of the Chemical Society, c, vol. 15, 1971, pp. 2696-2699, R. T. Coutts et al., "Acetylation and acetoxylation of 4-hydroxy-1,4-benzothiazin- and -benzoxazin-3(4H)-ones (cyclic hydroxamic acids)", *p. 2696, formula I, p. 2697, formula IIIf*.

Affiliated with

Also associated with

Rating

Alkanolaminoxy derivatives of 3,4-dihydro-2H-1,4-benzothiazin-3- does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alkanolaminoxy derivatives of 3,4-dihydro-2H-1,4-benzothiazin-3-, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkanolaminoxy derivatives of 3,4-dihydro-2H-1,4-benzothiazin-3- will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2318554