Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-09-23
1994-03-29
Killos, Paul J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546174, 546155, 560 10, 560 56, 562466, 562427, C07D21514, C07D21516, C07C 6976, C07C31500, C07C32100
Patent
active
052985113
ABSTRACT:
The invention concerns alkanoic acid derivatives of the formula I ##STR1## wherein Ar.sup.1 is optionally-substituted phenyl or naphthyl, or a 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur;
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patent: 4772703 (1988-09-01), Musser
patent: 4929626 (1990-05-01), Mohrs et al.
patent: 4960892 (1990-10-01), Kreft, III
patent: 4970215 (1990-11-01), Mohrs et al.
patent: 5098930 (1992-03-01), Edwards
patent: 5132328 (1992-07-01), Girodeau
Honda et al, "Synthesis of (.+-.)-Aphanorphine via an Aminylium Ion Intermediate", J. Chem. Soc. Perkin Trans. I, Mar. 1992, pp. 531-532.
I.C.I. Pharma
Imperial Chemical Industries plc
Killos Paul J.
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