Alkanesulfonamido triphenylethylenes

Details Alkanesulfonamido triphenylethylenes Alkanesulfonamido triphenylethylenes

1974-04-04

1977-01-04

Weinberger, Lorraine A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239B, 260239E, 260243B, 260240CA, 26029373, 2603265SF, 26032682, 260556A, 424246, 4242485, 424267, 424274, 424321, C07D29514

Patent

active

040012298

ABSTRACT:
Triphenylethylenes having an N-(dialkylaminoalkyl)alkanesulfonamide substituent in the one of the phenyl rings may be prepared from similarly substituted benzophenones by reaction thereof with a benzyl Grignard reagent followed by dehydration of the resulting triphenylethanol intermediate and if desired chlorination or nitration of the resulting product. The triphenylethylenes have estrogenic and post-coital antifertility action and are useful as intermediates for the preparation of other triphenylethylene compounds.

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