Alkaloid esters

Details Alkaloid esters Alkaloid esters

1975-12-29

1977-07-12

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424267, C07D45900

Patent

active

040353702

ABSTRACT:
Vasodilatory eburnamine-type alkaloid esters of the formula (I) ##STR1## and salts and quaternary derivatives thereof, wherein X.about.Y REPRESENTS A =CH=CH- or ##STR2## R represents a C.sub.1-6 alkoxycarbonyl group optionally substituted with a hydroxy group or with a halogen atom, further an alkenyloxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl group or an acylated primary alcohol group, especially apovincaninic acid ethyl ester, have been prepared by various methods of esterification.

REFERENCES:
patent: 3454583 (1969-07-01), Kuehne
Trojanek et al., Tetra. Letters 20, 702-706 (1961).
Kisfaludy et al., Chem. Abstracts 73:35598k (1970).

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