Alkaloid compounds, and pharmaceutical compositions containing t

Details Alkaloid compounds, and pharmaceutical compositions containing t Alkaloid compounds, and pharmaceutical compositions containing t

1988-03-03

1989-09-19

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514287, 546 48, 546 72, A61K 3147, C07D51316, C07D47106

Patent

active

048681911

ABSTRACT:
Novel alkaloid compounds that are derivatives of methaniminoetheno[d,e]acridine are derived from marine sponges of the genus Dercitus. These compounds and pharmaceutical compositions containing therapeutic effective amounts thereof are useful as antitumor and immunomodulatory medications.

REFERENCES:
patent: 4555572 (1985-11-01), Capps
patent: 4631149 (1986-12-01), Rinehart, Jr., et al.
Sakai et al., J. Am. Chem. Soc., vol. 108(20), pp. 6405-6405 (10/01/86).
Nakamura et al., Tetrahedron Letters, vol. 28, no. 6, pp. 621-624 (02/87).
Gunawardana et al., J. Am. Chem. Soc., vol. 110(14), pp. 4856-4858 (1988).

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