Alkali metal 8,9-dehydroestrone sulfate esters

Details Alkali metal 8,9-dehydroestrone sulfate esters Alkali metal 8,9-dehydroestrone sulfate esters

1992-12-03

1994-02-22

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

552503, 552625, 552626, A61K 3156, C07J 5300, C07J 3100

Patent

active

052887170

ABSTRACT:
This invention presents alkali metal salts of 8,9-dehydroestrone, its sulfate ester, and stable compositions thereof, as well as processes for their production. The sulfate ester salts are useful in estrogen replacement therapy.

REFERENCES:
patent: 3391169 (1968-07-01), Hughes et al.
patent: 3394153 (1968-07-01), Re
patent: 3644618 (1972-02-01), Holden
patent: 5210081 (1993-05-01), Raveendranath et al.
Roos, R. W., Journal of Chromatographic Science, vol. 14, No. 11, pp. 505-512 (1976).
McErlane et al., Journal of Pharmaceutical Sciences, vol. 66, No. 4, pp. 523-526 (1977).

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