Aliphatic compounds, their synthesis method, and utilization...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S255010, C514S426000, C514S428000, C548S557000, C548S558000, C548S568000

Reexamination Certificate

active

06949553

ABSTRACT:
The present invention relates to aliphatic compounds of the formula I, or stereoisomers thereof, or their pharmaceutically acceptable salts:wherein A represents an optionally substituted CH3CnH(2n-2m)— (wherein n denotes an integer of 4 to 22, and m represents an unsaturation number which is an integer of 0 to 7), l represents an integer of 0 to 10, s represents 0 or 1, provided that when s is 0, p+q=4 or 5, but when s is 1, p+q=3 or 4, and in each case, either p or q is an integer of 1 or more, R represents an alkyl group having 1 to 10 carbon atoms which may be straight-chain or branched-chain, and RArepresents hydrogen or an alkyl group having 1 to 10 carbon atoms which may be straight-chain or branched-chain, and their use in suppression of platelet aggregation, in suppression of inflammation, and in prevention and treatment of circulatory diseases.

REFERENCES:
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patent: WO 02/30872 (2002-04-01), None
Kiuchi et al., Chemical and Pharmaceutical Bulletin, 40(12), 3234-3244, 1992.
Wang et al., Experimental Studies of Structure and Inhibition Efficiency of Imidazoline Derivatives, Journal of Chinese Society for Corrosion and Protection, vol. 21, No, 2, pp. 116-122 (2001) (English abstract also provided).

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