Aligned scaffolds for improved myocardial regeneration

Details Aligned scaffolds for improved myocardial regeneration Aligned scaffolds for improved myocardial regeneration

2008-04-29

2009-08-25

Davis, Ruth A (Department: 1651)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Solid support and method of culturing cells on said solid...

C435S325000, C424S400000, C424S422000, C424S443000

Reexamination Certificate

active

07579189

ABSTRACT:
The present invention relates to a biocompatible, three-dimensional scaffold useful to grow cells and to regenerate or repair tissue in predetermined orientations. The scaffold is particularly useful for regeneration and repair of cardiac tissue. The scaffold contains layers of alternating A-strips and S-strips, wherein the A-strips within each layer are aligned parallel to each other and preferentially promote cellular attachment over attachment to the S-strips. Methods of producing and implanting the scaffold are also provided.

REFERENCES:
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patent: WO 00/34442 (2000-06-01), None
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