Alicyclic amides having a physiological cooling effect

Details Alicyclic amides having a physiological cooling effect Alicyclic amides having a physiological cooling effect

1980-08-11

1982-03-09

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

131276, 131335, 252110, 252522R, 424 45, 424 48, 424 73, 424156, 42424854, 424267, 424274, 426590, 426660, A61K 722

Patent

active

043189008

ABSTRACT:
Alkyl-substituted alicyclic carboxylic acids, esters and amides are disclosed having the property of stimulating the cold receptors of the nervous system of the human body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations.

REFERENCES:
patent: 2001046 (1935-05-01), Welch
patent: 3511914 (1970-05-01), Wolkoff et al.
patent: 3644653 (1972-02-01), Toheitcheff
Remington's Pharmaceutical Science, 13th Ed (1965), p. 855.
Wilson et al., Textbook of Organic Medicinal and Pharamceutical Chemistry, 4th Ed. (1962), pp. 111-112.
Chemical Abstracts, 7th Coll. Index (1962-1966) pp. 13780 e-13782S.
Chemical Abstracts 8th Coll. Index (1967-1971); pp. 18623s-18627s.
Chemical Abstracts 66:2275z (1967).
Chemical Abstracts 67:53774v (1967).

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