Alicyclic amides having a physiological cooling effect

Details Alicyclic amides having a physiological cooling effect Alicyclic amides having a physiological cooling effect

1974-12-09

1981-02-03

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

131 17R, 131144, 252110, 252522R, 424 45, 424 48, 424 73, 424156, 424320, 424324, 426590, 426660, 564123, 564189, A61K 722

Patent

active

042488591

ABSTRACT:
Alkyl-substituted alicyclic carboxylic acids, esters and amides are disclosed having the property of stimulating the cold receptors of the nervous system of the human body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations.

REFERENCES:
patent: 2001046 (1935-05-01), Welch
patent: 3511914 (1970-05-01), Wolkoff et al.
patent: 3644653 (1972-02-01), Tcheitcheff
Remington's Pharmaceutical Sciences, 13th Edition, (1965), p. 855.
Wilson et al., Textbook of Organic Medicinal and Pharmaceutical Chemistry, 4th Edition, (1962), pp. 111-112.
Chemical Abstracts 8th Collective Index, (1967-1971), vols., 66-75, pp. 18623s-18627s.
Chemical Abstracts 7th Collective Index, (1962-1966), vols. 56-65, pp. 13780s-13782s.
Chemical Abstracts, 66:2275z, (1967).
Chemical Abstracts, 67:53774v, (1967).

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