Alginate-based verapamil-containing depot drug form

Details Alginate-based verapamil-containing depot drug form Alginate-based verapamil-containing depot drug form

1991-01-24

1992-07-21

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

424464, 424468, 424469, 424474, 424475, 536 3, 514254, 514523, 514779, 514964, 514965, A61K 930, A61K 31275, A61K 922, A61K 926

Patent

active

051322951

ABSTRACT:
An alginate-based depot drug form for which the rate of release of the active substance in vitro can be adjusted very precisely is described.

REFERENCES:
Arzneim.-Forsch (Drig Res.) vol. 25, No. 8, Aug. 1975, D. Mayer et al.: "Entwicklung einer oralen Retard-form von Verapamil und Prufung der Resorption am narkotisierten Hund", pp. 1272-1275.
Journal of Controlled Release, vol. 3, No. 2-3, Mar. 1986, Elsevier Science Publishers B.V. (Amsterdam, NL), A. F. Stockwell et al.: "In Vitro Evaluation of Alginate Gel Systems as Sustained Release Drug Delivery Systems", pp. 167-175.

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