Aldoxime-substituted triazolium compounds useful in the treatmen

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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514383, 548269, C07C24908, A61K 3141

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active

048658375

ABSTRACT:
A therapeutically effective class of low toxicity aldoxime-substituted trazolium derivatives is disclosed which is effective in the treatment of living species poisoned by organophosphorus chemicals which inactivate the enzyme acetylcholinesterase. In vivo administration of therapeutically effective amounts of these low toxicity aldoxime-substituted triazolium derivatives has been found to save mice having inhibited acetylcholinesterase due to injection with lethal dosages of Soman.

REFERENCES:
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patent: 3852294 (1974-12-01), Hagedorn
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