Aldosterone antagonists

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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26023955R, A61K 3158, C07J 1700

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active

040815382

ABSTRACT:
A method for increasing the excretion of sodium by inhibiting the effect of mineralocorticoids, involving the administration to a patient of a therapeutically effective amount of an 11.beta.,18-oxidopregnane as an aldosterone antagonist.

REFERENCES:
patent: 2959586 (1960-11-01), Kerwin et al.
patent: 3178346 (1965-04-01), Wettstein et al.
Kagawa et al., Science, vol. 126 (1957) p. 1015.
Funder et al., Endocrinology, (99) p. 619 (1976).
Adam et al., Endocrinology (1978).

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