Aldose reductase inhibition by (Z)-5-fluoro-2-methyl-1-[[4-(meth

Details Aldose reductase inhibition by (Z)-5-fluoro-2-methyl-1-[[4-(meth Aldose reductase inhibition by (Z)-5-fluoro-2-methyl-1-[[4-(meth

1980-06-19

1981-12-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 3119

Patent

active

043071147

ABSTRACT:
Disclosed are new methods of using (Z)-5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3- acetic acid or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.

REFERENCES:
patent: 3647858 (1972-03-01), Hinkley
patent: 3654349 (1972-04-01), Shen et al.
patent: 3821383 (1974-06-01), Sestanj
PDR, 34 Edition, 1980, pp. 1147-1149.
Clin. Pharmacol. Ther, 21, 231 (1977), Ryan et al.

Affiliated with

Also associated with

Rating

Aldose reductase inhibition by (Z)-5-fluoro-2-methyl-1-[[4-(meth does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aldose reductase inhibition by (Z)-5-fluoro-2-methyl-1-[[4-(meth, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aldose reductase inhibition by (Z)-5-fluoro-2-methyl-1-[[4-(meth will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2367837