Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2007-12-10
2010-02-16
Ramirez, Delia M (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S121000, C435S252300, C435S189000, C435S193000
Reexamination Certificate
active
07662596
ABSTRACT:
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).
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Mori Ken-ichi
Nozaki Hiroyuki
Sugiyama Masakazu
Watanabe Kunihiko
Ajinomoto Co. Inc.
Meah MD. Younus
Oblon, Spivak McClelland, Maier & Neustadt, L.L.P.
Ramirez Delia M
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