Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2008-05-13
2008-05-13
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S121000, C435S106000, C435S193000, C435S069100, C435S252300, C536S023200
Reexamination Certificate
active
11362915
ABSTRACT:
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).
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Mori Ken-ichi
Nozaki Hiroyuki
Sugiyama Masakazu
Watanabe Kunihiko
Ajinomoto Co. Inc.
Meah Md. Younus
Prouty Rebecca E.
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