Aldolase, and method for producing optically active IHOG and...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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Details

C435S121000, C435S106000, C435S193000, C435S069100, C435S252300, C536S023200

Reexamination Certificate

active

07371549

ABSTRACT:
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).

REFERENCES:
patent: 2005/0004394 (2005-01-01), Kawahara et al.
patent: 2005/0009153 (2005-01-01), Sugiyama et al.
patent: 2005/0153405 (2005-07-01), Sugiyama et al.
patent: 2005/0244939 (2005-11-01), Sugiyama et al.
patent: 2006/0003426 (2006-01-01), Sugiyama et al.
patent: 2006/0172396 (2006-08-01), Sugiyama et al.
patent: 64-25757 (1989-01-01), None
patent: WO 03/056026 (2003-07-01), None
patent: WO 03/059865 (2003-07-01), None
patent: WO 03/091396 (2003-11-01), None
patent: WO 2004/018672 (2004-03-01), None
Whisstock, et al. Quarterly Rev. Biophy. 2003, pp. 307-340.
J.M. Stringfellow, et al., “Sequence of theEscherichia coliC Homoprotocatechuic Acid Degradative Operon Completed with that of the 2,4-Dihydroxyhept-2-ENE-1,7-Dioic Acid Aldolase-Encoding Gene (HPCH)”, Gene, 166, 1995, pp. 73-76.
Database UniProt Online, “Putative Aldolase”, Database Accession No. Q7WN18, Oct. 1, 2003, XP-002352627.
Database CA Online, “Mutagenesis and Crystal Structure of Pseudomonas Taetrolens Aldolase and the Use of the Enzyme for Production of Optically Activity IHOG”, Database Accession No. 2005:1044726, Sep. 29, 2005, XP-002352628.
U.S. Appl. No. 11/362,915, filed Feb. 28, 2006, Sugiyama, et al.
U.S. Appl. No. 11/362,915, filed Feb. 28, 2006, Sugiyama et al.
U.S. Appl. No. 11/561,665, filed Nov. 11, 2006, Sugiyama et al.

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