Albumin-solubilized hymenoptera venoms for vaccine use

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424 91, 424 88, A23J 700, C07G 700, C09H 0000, A61K 3936, A61K 3900

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044734956

ABSTRACT:
Hymenoptera venoms for vaccine immunization of human subjects are prepared by copolymerizing the venom with albumin using glutaraldehyde as the polymerizing reagent. Sufficient albumin is used to produce water-soluble copolymers of high molecular weight. The resulting water-soluble copolymers of molecular weights above 200,000 daltons are separated from the residual reagents, insolubles, and lower molecular weight polymers or copolymers.

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Mueller et al., Abstract 126, Abstracts of Papers, 36th Annual Meeting of the American Academy of Allergy, Feb. 18-20, 1980, Atlanta, GA.

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