Albumin microaggregates for radioactive scanning of reticuloendo

Details Albumin microaggregates for radioactive scanning of reticuloendo Albumin microaggregates for radioactive scanning of reticuloendo

1978-04-20

1980-10-07

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

260112R, 260122, 424 15, 424 9, A61K 2900, A61K 4300, C07G 700

Patent

active

042268460

ABSTRACT:
Microaggregates of a complex of (1) albumin, particularly human serum albumin and (2) a metal reducing agent, particularly a stannous reducing agent, preferably formed in the presence of a stabilizing ligand, which complex, when labelled with technetium-99m provides an excellent agent for imaging reticuloendothelial systems (RES), particularly the liver, spleen, and bone marrow; methods of making and using the same; a complex (physical or chemical) of technetium-99m with such microaggregates and methods of using such latter complex.

REFERENCES:
patent: 3720761 (1973-03-01), Hunter
patent: 3863004 (1975-01-01), Wolfangel
patent: 4071613 (1978-01-01), Hunter
Honda et al., J. of Nucl. Med., vol. 11, No. 10, 1970, pp. 580-585.

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