Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-01-23
2007-01-23
Weber, Jon (Department: 1652)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S363000, C435S069600
Reexamination Certificate
active
10976708
ABSTRACT:
The present invention provides a nitrosylated albumin variant wherein one or more amino acid residues of constituent amino acid sequences are substituted, or a different amino acid residue is inserted into a part of the constituent amino acid sequences. The albumin variant has sufficient antimicrobial property and permits application as various useful pharmaceutical compositions.
REFERENCES:
patent: 11-147838 (1999-06-01), None
patent: WO 96/30006 (1996-10-01), None
patent: WO 97/10265 (1997-03-01), None
Achilles Dugaiczyk, Simon W. Law, and Olivia E. Dennison (1982) Proc. Nat. Acad. Sci. U.S.A 79: 71-75.
Jonathan S. Stamler*, Omar Jaraki*, John Osborne*, Daniel I. Simon*, John Keaney*, Joseph Vita*, David Singeli, C. Robert Valerlt, and Joseph LoScalzo (1992) Proc. Natd. Acad. Sci. USA 89: 7674-7677.
Galliano M, Watkins S, Madison J, Putnam FW, Kragh-Hansen U, Cesati R, Minchiotti L. Eur J Biochem. (1998) 15; 329-34.
Ewing JF, Young DV, Janero DR, Garvey DS, Grinnell TA (1997) J Pharmacol Exp Ther. 283(2):947-54.
Richardson et al., “Potential therapeutic uses for S-nitrosothiols,” Clinical Science 102:99-105, 2002.
Ishima et al., J Pharm Soc Japan 123(Suppl. 4):161-164, 2003.
Jia et al.,Nature, 380: 221-226 (1996).
Miyamoto et al.,Biochimica et Biophysica Acta, 1477: 90-97 (2000).
Stamler et al.,Proc. Natl. Acad. Sci. USA, 89: 7674-7677 (1992).
Ishima et al.,J. Pharm. Soc. Jpn., 123, Suppl. 4: 161-164 (2003).
Akaike Takaaki
Otagiri Masaki
Kosson Rosanne
Leydig , Voit & Mayer, Ltd.
Nipro Corporation
Weber Jon
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