Albacarcins V and M

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 168, 536 181, 435119, C07H 704, C12P 1900

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active

045981450

ABSTRACT:
Novel antitumor antibiotics designated herein as albacarcins M and V are produced by fermentation of Streptomyces albaduncas strain C-38291 (ATCC 39151). The new antibiotics possess antibacterial activity and also inhibit the growth of mammalian tumors such as P388 leukemia in mice.

REFERENCES:
J. Antibiotics 34: 1544-1555 (1981) Balitz et al.
J. Antibiotics 34: 266-275 (1981) Nakano et al.
Agric. Biol. Chem. 44: 1157-1163 (1980) Hatano et al.
Can. J. Chem. 59: 3018-3020 (1981) Findlay et al.
Antibiotiki 22: 963-967 (1977) Gauze et al.
Antibiotiki 23: 675-676 (1978) Gauze et al.
Soviet Journ. of Bioorg. Chem. 4(8): 798-802 (1978) Kulyaeva et al.
Wei, et al., "The Jour. of Antibiotics", vol. XXXV, No. 4, Apr., 1982, pp. 545-548.
Wei, et al., "Chem. Abst.", vol. 97, 1982, p. 16702(u).
Weiss et al., "Chem. Abst.", vol. 98, 1983, p. 232(a).

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