Alanine transaminase enzymes and methods of use

Details Alanine transaminase enzymes and methods of use Alanine transaminase enzymes and methods of use

2011-03-29

2011-03-29

Rao, Manjunath N (Department: 1656)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S193000, C435S320100, C435S069100, C536S023200

Reexamination Certificate

active

07914985

ABSTRACT:
Novel alanine transaminase (ALT) polypeptides and the use thereof as a diagnostic marker to predict and monitor tissue damage and/or tissue malfunction. The ALT polypeptides are murine and/orrattusALT polypeptides and said ALT polypeptides are used to detect, predict and/or determine hepatic processes of an animal, particularly mice and/or rats.

REFERENCES:
patent: 4554101 (1985-11-01), Hopp
patent: 050-68548 (1993-03-01), None
patent: 10-075787 (1998-03-01), None
patent: WO 02/08400 (2002-01-01), None
patent: WO 02/55712 (2002-07-01), None
patent: WO 02/092768 (2002-11-01), None
SCORE search results from PCT/US2005/13019.
Q8BGT5 (ALAT2—MOUSE) UniProtKB/Swiss-Prot First appeared on Mar. 2003.
Q8K1J3—MOUSE accession Q8K1J3 Glutamic pyruvate transaminase (alanine aminotransferase 2 created on Oct. 1, 2002.
Mariko Ishiguro Complete Amino Acid Sequence of Rat Liver Cytosolic Alanine Aminotransferase. Biochemistry 30, 6048-6053, 1991.
Database UNIPROT, accession No. P25409, Alanine Aminotransferase, May 1, 1992, retrieved from PIR, 099.8% idenity in 495 amino acid overlap with SEQ ID No. 6.
Mariko Ishiguro et al.:Complete Amino Acid Sequence of Rat Liver Cytosolic Alanine Aminotransferase. Biochemistry 1991; vol. 30 No. 24: pp. 6048-6053.
Yang R.-Z, et al.cDNA Cloning, Genomic Structure, Chromosomal Mapping, and Functional Expression of a Novel Human Alanine Aminotransferase, Genomics, 2002, 79, 445-450.

Affiliated with

Also associated with

Rating

Alanine transaminase enzymes and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alanine transaminase enzymes and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alanine transaminase enzymes and methods of use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2708108