Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-11-28
2006-11-28
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S217120, C514S227500, C514S227800, C514S237800, C514S239200, C514S316000, C514S317000, C514S327000, C514S428000, C540S450000, C540S544000, C540S610000, C544S060000, C544S059000, C544S158000, C544S168000, C544S171000, C544S111000, C544S128000, C548S573000, C546S216000, C546S238000, C546S249000, C560S130000
Reexamination Certificate
active
07141560
ABSTRACT:
The present invention relates to alanine 2,6-dialkoxyphenyl ester derivatives having the general formula IThe invention also relates to pharmaceutical compositions comprising said derivatives, and to the use of these alanine 2,6-dialkoxyphenyl ester derivatives as hypnotics for the induction and maintenance of general anaesthesia.
REFERENCES:
patent: 1 102 011 (1968-02-01), None
patent: 1 160 468 (1969-08-01), None
patent: 00 05196 (2000-02-01), None
Brancaccio, G. et al., “Anestetici Locali,” II Farmaco, Ed. Sc., vol. 19 (1964) pp. 986-1002.
Zimmerman, S. A. et al., “Potentiation of γ-Aminobutyric AcidAReceptor CI15Current Correlates withIn VivoAnesthetic Potency1, ” J. Pharmacol. Exp. Therap., vol. 270, No. 3 (1994) pp. 987-991.
Franks, N. P. et al., “Molecular and cellular mechanisms of general anaesthesia,” Nature, vol. 367 (1994), pp. 607-613.
Tanelian, D. L. et al., “The Role of the GABAAReceptor/Chloride Channel Complex in Anesthesia,” Anesthesiology, vol. 78, No. 4 (1993) pp. 757-776.
Bennett David Jonathan
Hamilton Niall Morton
Akzo Nobel N.V.
Dubberley F. Aaron
Hess Susan
Nolan Jason M.
Vickrey David H.
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