Air lift bioreactor

Details Air lift bioreactor Air lift bioreactor

1985-03-15

1987-03-10

Scott, Samuel

Chemistry: molecular biology and microbiology

Miscellaneous

435241, C12M 104

Patent

active

046491171

ABSTRACT:
The disclosure provides an improved reactor/fermentor apparatus useful for carrying out cell culture and fermentation. The apparatus utilizes novel design features to provide optimum agitation of the cells while minimizing mechanical shear force. The reactor is composed of two chambers; an upper, wider chamber and a lower, small diameter chamber which are connected by inwardly sloping side walls. Agitation is accomplished by utilizing a gently flowing centrally disposed gas stream.

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patent: 4545945 (1985-10-01), Prave et al.
Feder et al., The Large-Scale Cultivation of Mammalian Cells, (1983), pp. 36-43, Scientific American 248, No. 1.
Onken et al., Airlift Fermenters: Construction, Behavior, and Uses, (1983), pp. 67-95, Advances in Biotechnological Processes 1.

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