AIMP2-DX2 and its uses

Details AIMP2-DX2 and its uses AIMP2-DX2 and its uses

2005-11-01

2008-12-02

Yu, Misook (Department: 1642)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S007230

Reexamination Certificate

active

07459529

ABSTRACT:
The present invention relates to a variant of AIMP2 lacking exon 2, named as AIMP2-DX2, which is specifically expressed in cancer cells. The AIMP2-DX2 protein and gene can be successfully used in the development of diagnosis and treatment of cancer.

REFERENCES:
patent: 2004/0175375 (2004-09-01), Kim et al.
Kim et al., “Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation,” Nat. Genet. 34:330-336, 2003.

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