Agonists of bitter taste receptors and uses thereof

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007100, C435S007210, C436S501000

Reexamination Certificate

active

07829299

ABSTRACT:
The present invention relates to agonists of the hTAS2R1, hTAS2R3, hTAS2R7 and hTAS2R40 bitter taste receptors, respectively, and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R1, hTAS2R3, hTAS2R7 or hTAS2R40 bitter taste transduction or bitter taste response.

REFERENCES:
patent: 6558910 (2003-05-01), Zuker et al.
patent: 6942874 (2005-09-01), McGregor et al.
patent: 7244584 (2007-07-01), Zuker et al.
patent: WO 01/18050 (2001-03-01), None
patent: WO 2004/029087 (2004-04-01), None

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