Aggrecanase molecules

Details Aggrecanase molecules Aggrecanase molecules

2006-10-24

2006-10-24

Steadman, David J. (Department: 1656)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S024000

Reexamination Certificate

active

07125701

ABSTRACT:
Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

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