Agglutrimetric platelet binding assays in blood

Details Agglutrimetric platelet binding assays in blood Agglutrimetric platelet binding assays in blood

1997-03-20

1999-07-13

Housel, James C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 78, 435 13, 436518, 436523, 436524, 436534, 436 69, 436164, G01N 33546, G01N 33557

Patent

active

059225513

ABSTRACT:
Methodology which avoids the problems associated with interference from whole blood is provided for instrumented determination of platelet binding function. Particularly, small particles to which fibrinogen is bound, and which contain an infrared light absorbing dye, are used to determine the binding of platelets in a whole blood sample to the fibrinogen. Agglutination of the platelets with the coated particles is determined by a change in infrared light absorption characteristics.

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