Agglutination assay method and element in dry system

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

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C436S523000, C436S534000, C436S535000

Reexamination Certificate

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06872577

ABSTRACT:
An agglutination assay method for quantitatively determination of an analyte in a liquid sample using particles bearing an anti-analyte. A non-fluid substance which retains the particles while suppressing the diffusion of the particles therein is used as a medium which is to be a place where the agglutination of the particles takes place. Upon analysis, a solation agent is added to the non-fluid substance medium to increase the fluidity of the non-fluid substance, thereby the particles bearing the anti-analyte can diffuse in the medium to cause the agglutination with the analyte. Preferably, the solation agent is added to the non-fluid medium together with the sample. The non-fluid substance medium containing the particle-labeled anti-analyte can be stored with a higher stability in the dry state. A dry analysis element for enabling such analysis method is also provided.

REFERENCES:
patent: 4620977 (1986-11-01), Strahilevitz
patent: 4753873 (1988-06-01), Beltz et al.
patent: 5547848 (1996-08-01), Shinoki et al.
patent: 6174700 (2001-01-01), Haynes et al.
patent: 6485703 (2002-11-01), Cote et al.

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