Chemistry: analytical and immunological testing – Involving antibody fragments
Patent
1987-08-27
1989-05-09
Marantz, Sidney
Chemistry: analytical and immunological testing
Involving antibody fragments
436520, 436533, 436534, 436805, G01N 33546, G01N 33555, G01N 33563
Patent
active
048290114
ABSTRACT:
A method of detecting the presence and/or amount (concentration) of an analyte in a sample is provided by forming a reaction medium containing (1) a sample; (2) a plurality of particles having a binding pair member bound to their surfaces; and (3) a monovalent complementary partner to the binding pair member to which is bound an analyte mimic or analyte binding partner; and detecting the presence or amount of agglutination of the particles in the reaction medium. In some cases a polyvalent receptor capable of binding to the analyte (and to the analyte mimic, if present) is also present in the reaction medium.
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Nisonoff Introduction to Molecular Immunology, Second Edition Sinauer Associates, Inc., Sunderland, Mass., 1984.
Biotrack Inc.
Marantz Sidney
Neeley Richard L.
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