Agglomerated hydrophilic complexes with multi-phasic release cha

Details Agglomerated hydrophilic complexes with multi-phasic release cha Agglomerated hydrophilic complexes with multi-phasic release cha

1993-07-20

1995-12-26

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424488, 424468, 514964, A61K 922, A61K 4736

Patent

active

054785740

ABSTRACT:
The present invention relates to a controlled release formulation which includes a therapeutically active medicament, a heterodisperse gum matrix, a pharmaceutically acceptable diluent, and an effective amount of a pharmaceutically acceptable surfactant and/or wetting agent to provide a multi-phasic controlled release of a therapeutically active medicament. The invention also relates to a method of preparing the same.

REFERENCES:
patent: 2993836 (1961-07-01), Nash et al.
patent: 3074852 (1963-01-01), Mayron
patent: 3079303 (1963-02-01), Raff et al.
patent: 3133863 (1964-05-01), Tamsey
patent: 3147187 (1964-09-01), Playfair
patent: 3388041 (1968-06-01), Gans et al.
patent: 3456049 (1969-07-01), Hotko et al.
patent: 3627583 (1971-12-01), Troy et al.
patent: 3629393 (1971-12-01), Nakamoto et al.
patent: 3639169 (1972-02-01), Broeg et al.
patent: 3726690 (1973-04-01), Schuppner, Jr.
patent: 3728445 (1973-05-01), Bardani
patent: 3773920 (1973-11-01), Nakamoto et al.
patent: 3836618 (1974-09-01), Stevens
patent: 3864469 (1975-02-01), Reiser et al.
patent: 3950508 (1976-04-01), Mony et al.
patent: 3963832 (1976-06-01), Hashimoto et al.
patent: 4013820 (1977-03-01), Farhadieh et al.
patent: 4072535 (1978-01-01), Short et al.
patent: 4167558 (1979-09-01), Sheth et al.
patent: 4199560 (1980-04-01), Gyarmati
patent: 4259314 (1981-03-01), Lowey
patent: 4308251 (1981-12-01), Dunn et al.
patent: 4361545 (1982-11-01), Powell et al.
patent: B14389393 (1985-10-01), Schor et al.
patent: 4424235 (1984-01-01), Sheth et al.
patent: 4439453 (1984-03-01), Vogel
patent: 4525345 (1985-06-01), Dunn et al.
patent: 4542011 (1985-09-01), Gleixner
patent: 4556678 (1985-12-01), Hsiao
patent: 4590062 (1986-05-01), Jang
patent: 4623394 (1986-11-01), Nakamura et al.
patent: 4692337 (1987-09-01), Ukigaya et al.
patent: 4695463 (1987-09-01), Yang et al.
patent: 4695467 (1987-09-01), Uemura et al.
patent: 4698101 (1987-10-01), Koivurinta
patent: 4698264 (1987-10-01), Steinke
patent: 4704285 (1987-11-01), Alderman
patent: 4717713 (1988-01-01), Zatz et al.
patent: 4755389 (1988-07-01), Jones et al.
patent: 4762702 (1988-08-01), Gergely et al.
patent: 4803077 (1989-02-01), Mitsuhashi et al.
patent: 4828836 (1989-05-01), Elger
patent: 4855143 (1989-08-01), Lowey
patent: 4968508 (1990-11-01), Oren et al.
patent: 5128143 (1992-07-01), Baichwal et al.
"Satiaxane Food-Grade Xanthan Gum", a booklet published by Satia.
"Hydrocolloids", a publication by Mero Rousselot Satia, p. 68.
"Xanthan Gum/Keltrol/Keltzan/a Natural Biopolysaccharide for Scientific Water Control", Kelco Division of Merck and Co., Inc., Second Edition, pp. 21-25.
"Formulating for Controlled Release with Methocel Cellulose Ethers", The Dow Chemical Company, .TM.1987.
Pharm. Ind., vol. 42, No. 6, 1980, Georgakopoulos, et al., "Locust Bean Gum as Granulating and Binding Agent for Tablets".
K. A. Khan, et al., "Pharmaceutical Aspects and In-Vivo Performance of Brufen Retard-an Ibuprofen SR Matrix Tablet", Proceed. Intern. Symp. Control. Rel. Bioact. Mater., 18 (1991), Controlled Release Society, Inc.
P. Giunchedi, et al., "Ketoprofen Pulsatile Absorption from `Multiple Unit` Hydrophilic Matrices, International Journal of Pharmaceutics", 77 (1991) 177-181.
H. M. Ingani, et al., 6th Pharmaceutical Technology Conference, vol. II, pp. 459-460, Canterbury, England, 1987.
A. C. Shah, et al., "Gel Matrix Systems Exhibiting Bimodal Controlled Release for Oral Drug Delivery", Journal of Controlled Release, 9 (1989) 169-175.
U. Conte, et al., "A New Ibuprofen Pulsed Release Oral Dosage From Drug Development and Industrial Pharmacy", 15 (14-16), 2583-2596 (1989).

Affiliated with

Also associated with

Rating

Agglomerated hydrophilic complexes with multi-phasic release cha does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Agglomerated hydrophilic complexes with multi-phasic release cha, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Agglomerated hydrophilic complexes with multi-phasic release cha will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1367398