Agents for the treatment of severe pain and preparation of said

Details Agents for the treatment of severe pain and preparation of said Agents for the treatment of severe pain and preparation of said

1990-08-14

1992-12-22

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424458, 424451, A61K 964

Patent

active

051733048

ABSTRACT:
The agents for the treatment of conditions of severe pain, and especially of tumor pain and post-operative pain, consist of soft gelatin capsules containing from about 30 to about 50 parts by weight of ibuprofen and from about 1.5 to about 4 parts by weight of codeine and/or physiologically compatible salts thereof, partially dissolved and partially suspended in about 68.5 to about 46 parts by weight of polyoxyethylene-polyoxypropylene-diol or in a mixture comprising about 30 to about 76 parts by weight of polyoxyethylene-polyoxypropylene- diol or polyethylene-glycol or polypropyleneglycol and from about 7 to about 40 parts by weight of a physiologically compatible surfactant.

REFERENCES:
patent: 4571400 (1986-02-01), Arnold
patent: 4839176 (1989-06-01), Pankhania et al.
patent: 4844907 (1989-07-01), Elger et al.
patent: 4894234 (1990-01-01), Sharma et al.
patent: 4923898 (1990-05-01), Sunshine et al.

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