Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-12-22
1998-05-19
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514326, 514408, 514421, 514422, 514424, A61K 31445, A61K 3140
Patent
active
057536910
ABSTRACT:
The pharmaceutical use of 1-cinnamoyl-2-pyrrolidinone derivatives having the activities to inhibit the production of IL-1.beta. and the release of TNF.alpha.. Those derivatives are useful in the treatment or prophylaxis of the diseases such as chronic rheumatism and sepsis.
REFERENCES:
Database WPI, Derwent Publications Ltd., AN 90-070409, XP002001828 & JP-A-02 022 263, (Meiji Seika Kaisha), 25 Jan. 1990, Abstract.
CA: vol. 115. No. 7 71387k Giannessi et al., Aug. 1991.
Ariga Masato
Hatanaka Shigeo
Katsuyama Koichi
Momose Kenichi
Saito Yukio
Criares Theodore J.
Nisshin Flour Milling Co. Ltd.
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