Agents for improving lipid metabolism and reducing high...

Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Milk or colostrum

Reexamination Certificate

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C514S002600, C514S021800

Reexamination Certificate

active

06929806

ABSTRACT:
A milk-derived basic protein fraction and a basic peptide fraction are provided for use as an effective component for agents for improving lipid metabolism and reducing high blood pressure which can be administered orally, are effective with a relatively small dosage, have good taste and are stable during storage.

REFERENCES:
patent: 5866418 (1999-02-01), Ballard et al.
patent: 6183784 (2001-02-01), Read et al.
patent: 0 786 473 (1997-07-01), None
Steve L. Taylor, “Handbook of Milk Composition,” Academic Press Inc. p. 467 1995.
Anne Pihlanto, et al., “Angiotensin 1-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides,” Journal of Dairy Research (2000) 67 pp. 53-64.
Amhar Abubakar, et al., “Structural Analysis of New Antihypertensive Peptides Derived from Cheese Whey Protein by Proteinase K Digestion,” J. Dairy Sci 81 pp. 3131-3138 1998.
Masafumi Maeno, “Identification of an Antihypertensive Peptide from Casein Hydrolysate Produced by a Proteinase fromLactobacillus helveticusCP790,” J Dairy Sci 79 pp. 1316-1321 1996.
Naoyuki Yamamoto, et al., “Antihypertensive Effect of the Peptides Derived from Casein by an Extracellular Proteinase fromLactobacillus helveticasCP790,” J Dairy Sci 77 pp. 917-922 1994.

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