Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2005-12-16
2010-06-22
Yaen, Christopher H (Department: 1643)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C424S130100
Reexamination Certificate
active
07741275
ABSTRACT:
The present invention provides agents for inhibiting the proliferation of cancer cells, wherein the agent inhibits the biological activity of hCAP18/LL-37. In a preferred embodiment, the agent alters the transcription, translation and/or binding properties of hCAP18/LL-37. Preferably, the agent is selected from the group consisting of short interfering RNA (siRNA) molecules, antisense oligonucleotides and compounds with binding affinity for hCAP18/LL-37. The invention further provides methods for inhibiting the proliferation of cancer cells in a patient, as well as methods and kits for diagnosing cancer.
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Heilborn Johan D et al., Int
Heilborn Johan
Nilsson Margareta Frohm
Ståhle Mona
Weber Gunter
Birch & Stewart Kolasch & Birch, LLP
Lipopeptide AB
Yaen Christopher H
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