Agents and method of production thereof

Details Agents and method of production thereof Agents and method of production thereof

1985-05-10

1992-04-21

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549265, 435119, 4352535, 435886, C07D31306, C12P 1711, C12N 120

Patent

active

051069946

ABSTRACT:
This invention relates to new agents designated LL-F28249.alpha., LL-F28249.beta., LL-F28249.gamma., LL-F28249.delta., LLF28249.epsilon., LL-F28249.zeta., LL-F28249.eta., LL-F28249.theta., LL-F28249.iota., LL-F28249.kappa., LL-F28249.lambda., LL-F28249.mu., LL-F28249.nu., and LL-F28249.omega., to their production by fermentation, to methods for their recovery and concentration from crude solutions, to processes for their purification and to pharmaceutically and pharmacologically-acceptable salts thereof. The present invention includes within its scope the biologically pure culture which produces there agents, derived from a newly-discovered and previously uncultured microorganism, Streptomyces cyaneogriseus subsp. noncyanogenus, NRRL 15773.

REFERENCES:
patent: 4200581 (1980-04-01), Fisher
patent: 4285963 (1981-08-01), Arison
patent: 4408059 (1983-10-01), Smith
patent: 4851428 (1989-07-01), Asato et al.
patent: 4857544 (1989-08-01), Tamura et al.
patent: 4876272 (1989-10-01), Asato et al.
patent: 4886828 (1989-12-01), Asato et al.
Carter et al., J. Chem. Soc., Chem. Commun, 1987, pp. 402-404 (Comm 1468).
Carter et al., J. of Antibiot., vol. 41, 1988, pp. 519-529.

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